Human growth hormone is the most sought after substance in the bodybuilding world. It can build muscle mass and burn fat at the same time. Moreover, it maintains the health of bones and joints. But the price of an efficient cycle of HGH is huge, and some serious side effects may also occur.
In the human body, growth hormone (HGH) is produced by the pituitary gland. It is found in very large quantities during adolescence, when it promotes tissue generation, protein storage and consumption of subcutaneous fat. With age, the endogenous levels of this hormone decrease steadily, remaining present in the body in very small quantities, with very little visible effects. In the body, the growth hormone structure consists of a range of 191 amino acids.
Before the pituitary gland releases growth hormone, the growth hormone that releases the growth hormone and somatostatin are released by the hypothalamus, which determine the amount of growth hormone released by the pituitary. There are many factors that influence the release of growth hormone, including nutrition and training.
After being isolated by scientists, this hormone has been shown to have fantastic therapeutic properties, especially in the case of pituitary deficiency.
It was first isolated in 1956, and its structure was identified in 1972. In the 1980s, the first drugs that contained growth hormone appeared. The only source of growth hormone was the pituitary gland of human bodies. But this method of drug production had a short life, because because of these drugs patients could become infected with a very rare brain disease, the disease that was fatal. Nowadays all the growth hormone preps are synthetic. It is almost impossible to find on the market old products like Grorm.
The use of growth hormone has become more and more widespread in the sports world due to the many beneficial effects. His promoter (as is the case for many other substances used today in bodybuilding) was Dan Duchaine.
Growth hormone is a protein that stimulates the body's cells to grow in size, but also to divide faster, increasing their number. It also improves the passage of amino acids through the cell membrane, and increases their conversion rate into proteins. In other words, it creates an anabolic environment in the body. Furthermore, growth hormone decreases the rate at which cells use carbohydrates for energy, favoring the use of fats. Thus, growth hormone builds muscle mass while burning fat.
Increases caused by growth hormone include skeletal muscle and in addition to the eyes and brain all other organs.
How Anabolic is the Growth Hormone? In one study, the endurance athletes at rest, who used HGH, were in an anabolic state. In other words, you can run marathons and still build muscle.
Growth hormone is released by the pituitary gland through rhythmic pulses, during sleep, by two peptides: the growth hormone that releases growth hormone and somatostatin. These two peptides are secreted in turn. As you can imagine, the hormone that releases growth hormone is the one responsible for stimulating the pituitary gland (logically!).
Growth hormone can also stimulate cartilage recovery and strengthening (an advantage for those who work with very heavy weights). But for this process, there is a need for a mediator, somatomedin (IGF - the insulinostimulatory growth factor), which is secreted from the liver in response to growth hormone. IGF is the one that promotes cartilage recovery. The highest levels of IGF-1 occur within 20 hours of growth hormone administration.
Even though HGH needs IGF to restore cartilage, it can by itself increase the length of the bones; it also has a beneficial effect on erythropoietin, which further influences anabolism but also endurance.
As there is negative feedback to everything in the body, so is the case with growth hormone; and involves IGF. When the liver secretes IGF-1 a signal is transmitted to the hypothalamus and the pituitary gland to stop growth hormone production.
Now something interesting: even if the growth hormone is a very good muscle mass builder and a good fat burner, it is a bad choice when you want to increase your strength. It may seem illogical, those who use it claim the opposite. But it is usually used in conjunction with anabolic androgenic steroids and other stimulants, the strength increasing from these.
Although it is forbidden to use it in the sports world, there are no tests to detect HGH through urine analysis. The only method by which HGH delivery can be detected is by blood collection.
The extent to which HGH helps a sportsman has been the subject of a long dispute. Some claim that it is the most anabolic substance, capable of amazing things, being able to offer increases in muscle mass and burning of the fat layer in very short periods of time. Because it is used only by professional competitors who can afford such expensive substances, an even greater aura of mystery surrounds HGH. Many say that the "tons" of muscle presented to Mr. Olympia by competitors are 100% due to the use of growth hormone. There are also those who say that it is a waste of money and time, that it has no anabolic properties and the very high price makes it totally useless in front of steroids. With so many opinions divided on who should we believe?
First we need to understand why the results vary so much. It seems that the most logical is the extremely high price. The technology by which it is produced is elaborated, the production costs are high, reaching a sportsman who can cost impressive amounts per day HGH administration. Estimating a price is irrelevant, prices often changing, but it is a lot of money. Most do not allow such amounts and compensate by administering small doses. This will lead to very small or nonexistent effects. If you cannot afford a full HGH cure, you should not try at all. The high cost is mainly due to the fact that the efficiency of growth hormone is seen on the long side, from 4 months upwards. Many claim that its effects are only visible after 2 months. There are many who use it in cures for 6 months, even for one year.
Administration of growth hormone
Doses are 2-6 U.I. (international units) to achieve the best results, but there are people who also use higher doses. But the ideal dose is calculated according to the weight of each one. The most commonly used doses by athletes are 2 - 4 U.I. It was believed that daily administration is very important, because the HGH has a short lifespan. But subsequent studies have rejected this hypothesis. The best way to administer it is one day yes no. Thus, the natural pulses of growth hormone release are better imitated, and the over-saturation of the receptors is avoided, leading to better long-term results.
The best thing to do is to give yourself a day but no; on the day it is administered, it is done in two halves, in the morning after waking and in the evening before bed. The optimal dose for administration is 0.028 U.I./ kg body. So, someone who weighs 90 kilos will administer 2.5 U.I. twice daily, for a total daily dose of 5 U.I.
The maximum concentration in the blood appears after 4-6 hours after the injection and has a half-life of 30 minutes. This certainly makes maintaining constant HGH levels in the blood difficult. Also the effects are more pronounced when used for long periods of time, often several months. It can also be used for shorter periods, but especially when tracking the loss of the fat layer. For this a cycle of at least 6 weeks should be followed. It generally has a slow action and results are visible after 8-12 weeks.
It can be administered intramuscularly or subcutaneously (the last variant being the most commonly used). Subcutaneously has an absorption of 75% and intramuscular 63%. Subcutaneous injection also results in fat loss where it is made, which makes it necessary to change the injection site every time for a symmetrical appearance of the body. It seems that most agree when it comes to the fat burning properties of HGH. They are the most pronounced and are seen the fastest, without very high doses.
Other substances can be used together with growth hormone for best effects. It appears that the body also needs a higher amount of thyroid hormones, insulin and androgens when HGH levels are high. For starters, adding hormones to the thyroid gland will increase the thermogenic effect of the cycle. It can be given Cytomel or Synthroid (T3 or T4). And insulin is welcome in such a cycle, especially for its anabolic properties. Steroids are also required for HGH to reach its anabolic potential. Androgen is preferable, such as testosterone or trenbolone. The androgen effect is welcome because it promotes anabolism by means other than the growth hormone. This combination of HGH, anabolic, insulin and T3 is highly synergistic, being the best way to build muscle mass and lose fat. However, it must be borne in mind that thyroid hormones and insulin are potent substances that involve certain additional risks. Strong and risky combinations such as the above are not recommended for professionals, much less for amateurs, and in no case without specialized supervision.
Growth hormone also comes with certain side effects that may occur, depending on the sensitivity of each one. Thinning or thickening of the bones, especially in the hands, feet and forehead; enlargement of internal organs; hypoglycemia due to induction of insulin resistance; carpal tunnel syndrome. However, these risks are low, such problems being rarely reported among athletes who use moderate doses, even if they do it regularly and for long periods of time. But if there is a change in the structure of the bones, skin texture or other alarming signs, the administration should be stopped immediately forever.
Gynecomastia or fluid retention are also possible with growth hormone utilization. In fact, a common side effect is water retention around the ankles and wrists, along with joint and headaches. They appear mainly at the beginning of the cycle and gradually disappear.
Other side effects that may occur are: reduction of thyroid hormone T3 levels, nausea, dizziness, respiratory infections, numbness of the skin.
Another possible effect is the irritation of the injection site and the appearance of small swelling. Many inject their growth hormone into the abdomen, being the only hormone that can lead to local fat burning. Abuse of growth hormone, the use of very large doses or its use over a long period of time, can lead to enlargement of the hands, feet, jaw and internal organs. It can also cause type II diabetes due to increased insulin resistance.
Don't get me wrong, growth hormone is effective; except that there are no compromises. Either you are willing to spend as much as it takes to complete a cycle, or you are focusing on something else! Dose reduction and shortening cycles are not viable options.
Due to the high price, many growth hormone falsifications have appeared. TO AVOID THESE FALSE ACCESS TO OUR WEBSITE BODYROIDS.COM A good part of what is on the black market are in fact HCG "wrapped" in HGH packaging. Such products can be detected by a pregnancy test purchased from the pharmacy. These tests work by detecting the HCG in the urine, present during pregnancy. In the case of
we want to find out if HCG is in our vials of HGH. One week after starting the cycle, inject 1 ml of growth hormone before bedtime. When you wake up take the pregnancy test. If it comes out positive it means that you have been fooled and that you are actually taking HCG and not growth hormone.
Growth hormone (like HCG) is packed in two separate vials, one containing a sterile solution, the other a powder. The contents of the two ampoules are mixed before being injected. Synthetic growth hormone is perishable, and should be kept refrigerated.