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MELANOTAN-2 PEPTIDES

MELANOTAN-2 PEPTIDES

Melanotan II is a substance used by bodybuilders to tan without sun or sun exposure. Furthermore, it can increase the libido and increase fat burning.
Active substance: PT-141
Melanotan II is an analogue of the hormone-stimulating hormone alpha-melanocyte peptide (MSH). This preparation confers a therapeutic tan, lowering the risk of skin cancer; also has an important effect in increasing libido in men and women. In addition, it also has the effect of lowering body fat. Melanotan II is a cyclic analog of alpha-MSH with the amino acid sequence Ac-Nle-cyclo [Asp-His-D-Phe-Arg-Trp-Lys] -NH2.
Melanotan II is part of a group of hormonal peptides called melanocortins. Melanocortins are multifunctional hormonal peptides that regulate a number of physiological functions in the body, including sexual functions. Therefore, Melanotan II can improve sexual functions in men (erectile activity) but also in women (increased libido and genital arousal). Unlike other sexual stimuli, Melanotan II acts in the brain, using a method very close to the natural one, with minimal or no side effects.
Melanotan II was accidentally discovered at the University of Arizona in 2005. He was tested on several subjects, both healthy and suffering from erectile dysfunction, but did not respond to Viagra. The response to PT-141 was higher, statistically, which suggests that this preparation may have wide applications in the treatment of erectile dysfunction.
In addition to the tanning effects and increased libido, it has been noted that Melanotan II can also reduce adipose tissue and suppress appetite.
In bodybuilding it is used mainly for its tanning properties, without exposing you to the risks associated with solariums, or prolonged exposure to the sun. But its other properties make it attractive. It is not yet approved for human use, and can only be purchased on the black market.
Melanotan II signals the release of more leptin from fat cells, a hormone responsible for lipolysis. In addition, it reduces insulin resistance and increases the oxidation of fatty acids. But the main mechanism by which the fat layer is reduced is the lack of appetite, and thus greatly reduces the caloric intake.
It is administered by subcutaneous injections. Doses differ from person to person, depending on weight, skin, etc. The standard dose is 0.02 mg / kg. The first part of the administration is loading, and then it goes on a maintenance dose.
The loading phase is two weeks, in which 0.5 mg or 1 mg daily is administered. Two injections can be made daily, dividing the daily dose into two. After the loading period, it is administered every 3 or 4 days, the dose remaining the same (0.5 -1 mg / day). Most start at a low dose of 0.25 mg per day and gradually increase (by 0.25 mg per day - that is, if the side effects, especially nausea, raise no problem) up to the dose of 1 - 1.5 mg per day. When the desired bronze level is reached, the administration is reduced, entering the maintenance phase.
It is found in powder form, usually 10 mg, which is prepared with bacteriostatic water to obtain the injectable form. The powder should be stored in the freezer or refrigerator in order not to degrade; however, the degradation lasts a few weeks, so don't worry if it is sent to you by post or other method, and it doesn't stay cold all the time.
Depending on the amount of water used, the concentration of the solution will result. For example, a 10 mg vial of Melanotan II combined with 1 ml of bacteriostatic water will produce a solution with a concentration of 10 mg per milliliter. This means that in order to administer 1 mg of Melanotan II you must inject 0.1 ml of solution. And since the starting doses are less than 1 mg, it would mean a smaller amount of solution, which is very difficult to accurately extract in the syringe. So it is good to use a larger quantity of water in preparation.
You can mix 4 ml of bacteriostatic water with Melanotan II powder, to obtain a concentration of 1 mg to 0.4 ml or even equal parts, 10 ml water to 10 mg powder, to obtain a concentration of 1 mg per milliliter. After mixing the water with the powder, the resulting solution must be kept in the refrigerator. Can withstand refrigeration for up to 4 or even 5 weeks.
    For injections, 1 "long needles with a diameter of 25 gauge, or insulin syringes are used.

The main side effects are due to its tanning properties and nausea. Those with moles should know that they will turn dark, especially in the area of ​​the face and shoulders and back. Also, before and after using Melanotan II take care not to damage the skin, because they will heal so, staying permanently there. Also, avoid long exposures to the sun or other sources of ultraviolet during the Melanotan II cycle, and use protective creams with high factor (over 30) on the neck, hands and face (areas that contact the sun most often).
   Other side effects:
    nausea (at 85% of users);
    redness of the face (75% of users);
    fatigue (in 44% of users);
    vomiting (in 26% of users);
    injection site reactions (in 13% of users);
    DO NOT affect renal and hepatic functions;
Side effects decrease as the Melanotan II cycle progresses. Most users will experience at a certain level side effects, the main ones being nausea, appetite suppression and redness of the face. These manifest within minutes after administration and may last up to several hours.
Another side effect is the periods of intense libido growth, accompanied by uncontrolled erections. Even though it may seem funny or even desirable, in a social context it can become an embarrassing problem.
Again, it is important to start from small doses and gradually increase them to minimize the side effects.
Some people may also have freckles, but they will not be seen because of the tan. After the cessation of Melanotan II administration they will disappear.
A high dose of Melanotan II should not be given at once, because the side effects are dependent on the amount of PT-141 in the blood; therefore 1-2 or 3 smaller administrations per day are recommended. It is an important aspect, because it is a foreign substance in the body, it can trigger an anti-allergic response, which can lead to anaphylactic shock in extreme cases. Antiallergic medicines can be used to reduce the risk. Allergic reactions are rare, but we also mentioned this aspect for more sensitive individuals.
As I said earlier, Melanotan II is currently undergoing laboratory tests to develop commercial products. But as this substance has attracted the attention and aroused the interest of bodybuilders and other people who want a fast and good quality tan, as well as its other properties, the black steroid market has adapted and started offering this product. Most peptides originate from China.
There is another variant of this peptide, Melanotan I, which has some minor side effects, but is not as strong. In addition, the effects of sexual arousal and erections are attributed only to Melanotan II.

12.12.2019