THYMOSIN Beta-4 (TB-500)
Thymosin Beta-4 is a recently discovered peptide, which has huge potential in recovering athletes after injuries and in recovering damaged joints.
Recently a new substance has emerged in the world of horse racing. It's about Thymosin Beta-4, also called TB-500. What does this have to do with people, and athletes or bodybuilders? Many! Thymosin Beta-4 is a unique peptide, which was recently discovered in the thymus, a gland in the human body. Since the initial discovery, several types of thymosin have been discovered in various tissues in the body.
A place where Thymosin Beta-4 is found, and is of interest to bodybuilders and sportsmen, are the muscles, both the smooth ones (like the heart muscle) and the skeletons. When a trauma occurs, Thymosin Beta-4 is released to heal that trauma. It also works to prevent the formation of adhesions. This means the formation of smaller and more flexible scars. The TB-500 is the Thymosin Beta-4 synthetic variant, which does exactly the same thing as the natural variant.
What makes TB-500 more concrete? It increases blood flow, maintains healthy blood vessels, increases the rate of skin healing from abrasions, maintains and rebuilds joints and reduces inflammation. Medically, it is of particular interest in treating heart problems, and is supposed to restore cardiac muscle after a heart attack. It also appears to have protective properties for neurotransmitters, being useful after a stroke.
Why is it of interest to bodybuilders and any athlete? It can increase muscle endurance, muscle strength, flexibility and decrease inflammation in the body. In other words, it is very useful for the recovery after injuries, and for maintaining the health of the joints in particular. This includes a significant improvement of the lumbar area, a part of the body affected by many people who practice sports, especially involving the use of heavy weights.
Not much is known about the substance itself. It is still in an experimental stage, and the access of amateur athletes and bodybuilders to it is limited, both by the low availability and the high price.
Those who used it did not report any side effects, nor the tests performed on animals, but also on humans (intravenously) did not show any adverse symptoms or toxicity. But it is an experimental drug, recently discovered, so it is not yet known the full mode of action and the effects in the medium or long term.
It can be given intravenously, intramuscularly or subcutaneously. The last two variants are those used by athletes. Most of them administer it subcutaneously; There is a theory that intramuscular administration near a severely affected joint is more beneficial, but it is just speculation, unsupported by any scientific evidence.
The results of Thymosin Beta-4 administration are slowly manifested, which is why prolonged administration is required. First, a charging phase is followed, and then a maintenance phase. The loading doses range from 4 mg to 10 mg / week, divided into two weekly injections, and in the maintenance phase 4-10 mg / month, through two monthly injections. The charging phase lasts 4-6 weeks, and then the maintenance for several months.
The doses mentioned above are those used by various athletes, amateurs or professionals. They were calculated by comparison with the doses administered to racing horses or race tracks; therefore they are not very accurate. A more accurate calculation, after certain formulas of calculations for the conversion of animal doses to human doses, would result in a dose of 0.084459 mg / kg TB-500. Therefore, someone weighing 90 kg would need 7.66 mg / week. But this is also a rough approximation.
Most likely, more accurate doses will be established after several years of use and experiences with this new substance. Bodybuilders use it either alone or in combination with IGF-1 Long R-3 or CJC-1295 or GHRP-2/6.
Thymosin Beta-4 has enormous potential in both medicine and sports. Unfortunately, in some countries (such as Australia), TB-500 has already reached the table of anti-doping commissions, and may be banned in most sports.