About Steroids

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Frequency: A dose of ~3g leucine/meal is required to saturate the mTOR signalling pathway & trigger MPS . Once stimulated, MPS then peaks after 2hrs before declining to baseline after ~3-4hr . Thus, for the goal of maximizing the anabolic response from PRO ingestion, the above suggests that one should avoid spacing meals out too closely & far away from each other. Therefore, considering ~3-4hr be the duration MPS takes to rise & fall, in a typical 14hr eating window (8am-10pm) 3-4meals/day spaced out at 4hr intervals has shown to MAXIMISE the anabolic response & thus LBM gain . However, note that to effectively maximize the anabolic response, its necessary you reach that key 3g LEU threshold AT EACH MEAL. In practical terms this means to consume ~30–40g quality PRO/meal . Also 3-4 meals has shown to result in higher satiety ratings over higher & lower feeding frequencies thus another benefit of the 3-4meal rule
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So, 30-40g, 3-4x/dy seems best to wanting OPTIMISE gains however, before stressing out, the most important thing is to eat 1.2-2g/kg TOTAL
03.04.2020