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Dostinex (Cabergoline)

8 tabs (0.5mg/tab)
55.00$
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DOSTINEX, tablets, 0.5 mg | cabergolinum
Active substance: cabergolinum
Manufacturer: Pfizer ..
ATC class: [G02CB]: urinary tract and sex hormones >> other gynecological preparations >> other gynecological products >> prolactin inhibitors
Category: Lactation stop
Pharmaceutical group: prolactin inhibitors
Type: Tablets
The name of the drug is Dostinex. Each tablet contains 0.5 mg of cabergoline as an active substance.

Cabergoline belongs to the group of drugs that inhibit prolactin.
directions:
Dostinex is used to prevent or stop breastfeeding in the period immediately following the birth of the baby or may stop breastfeeding if you are already breastfeeding. Dostinex may also be used for other conditions due to increased prolactin concentration, such as the absence or irregularity of menstrual cycles, excessive secretion of milk or infertility, or, in men, to treat impotence or decreased sexual libido.
contraindications:
Do not take Dostinex
- if you are allergic (hypersensitive) to cabergoline, ergot alkaloids (eg bromocriptine) or any of the other ingredients of Dostinex.
- you will be given Dostinex for a long time and if you have or have had fibrotic reactions (scar tissue) that affects your heart
Administration:
Always take Dostinex exactly as your doctor has told you. You should talk to your doctor or pharmacist if you are not sure.
Dostinex tablets are swallowed, preferably during meals.
The usual dose for lactation prevention is 1 mg (2 tablets) on the first day after you are born.
The usual dose for stopping lactation is half a tablet twice daily for 2 days.
In order to lower the concentration of prolactin in certain diseases, Dostinex is usually taken once or twice a week (for example, on Mondays, or on Mondays and Thursdays). Initial doses are usually small (half a tablet or one tablet a week). The doctor will tell you if you need to take a higher dose.
Dostinex is not recommended for patients under 16 years of age.
If you take more Dostinex tablets than you should
If you take too many tablets at once, call your doctor or go to your nearest hospital immediately.
If you forget to take Dostinex
Do not worry. Take the next dose as soon as you remember. Do not take a double dose to recover the missed dose.
If you stop taking Dostinex
Follow the treatment for as long as the doctor recommends.
Women wishing to avoid pregnancy should use mechanical contraceptive devices, even after discontinuing treatment with Dostinex and until anovulation (lack of fertility) is established.
Pregnancy should be avoided for one month after discontinuation of Dostinex.
Action:
Dostinex prevents or stops lactation (the production of breast milk) by decreasing the concentration of the hormone prolactin in the body. By lowering the prolactin concentration, Dostinex can also restore fertility.
Composition:
The active substance is cabergoline. One tablet contains 0.5 mg cabergoline.
The other components are anhydrous lactose and leucine.
Precautions:
Before treatment with Dostinex, tell your doctor if:
- suffer from kidney or liver disease - your doctor will perform a series of tests;
- you have high blood pressure, edema (swelling of the ankles, face or hands) and kidney problems during or after pregnancy;
- you had mental disorders during pregnancy or after giving birth to a child;
- suffer from any cardiovascular or pulmonary disease;
- suffering from Raynaud's syndrome (the circulation of the blood in the fingers is affected by the cold and the fingers become pale or crumble, with sensation of tingling, numbness or burning in the respective areas);
- suffer from peptic ulcer (abdominal pain when you are hungry);
-You have gastrointestinal bleeding (the stools become black or shed with blood);
- suffer from high blood pressure or take medicines to fight high blood pressure.
-You have Parkinson's disease and you suddenly fell asleep.
-if you have or have had fibrotic reactions (scar tissue) affecting your heart, lungs or abdomen. If you are given Dostinex for a long time, before treatment, your doctor will check if your heart, lungs, or kidneys are in good condition. He / she will perform an echocardiogram (an ultrasound examination of the heart) before starting treatment and at regular intervals during treatment. If fibrotic reactions occur, treatment will be discontinued.
Because the drug contains lactose, administration is not recommended in patients with hereditary intolerance to galactose, Lapp lactase deficiency or glucose-galactose malabsorption.

Warning:
Driving and using machines
During treatment, especially during the first few days, you should pay attention to your ability to react because it may be low, you may have drowsiness or you may even fall asleep suddenly.
If these events occur, do not drive or use machines.
Important information about some of the components of Dostinex
The tablets also contain lactose. If your doctor has told you that you have an intolerance to some sugars, contact him before you start taking this medicine.
Side effects:
Like all medicines, Dostinex can cause side effects, although not everybody gets them.
The most common can be:
- dizziness
- constipation
- headaches
- depression
- nausea
- muscle weakness
- abdominal pain
- tingling or tingling sensation
- vomiting
- nasal bleeding
- sensation of "heat waves" with the sudden redness of the face
- impaired vision
- increasing the frequency of heartbeats
- lowering blood pressure, sometimes up to fainting
- fatigue / drowsiness
- breast pain
- indigestion or other digestive disorders - cramps
Very common side effects (affecting more than one in ten people): heart valve disorders and related conditions, such as inflammation (pericarditis) or fluid leakage into the pericardium (pericardial effusion).
Early symptoms may be one or more of the following manifestations - shortness of breath, shortness of breath, chest or back pain, and swelling of the legs. If you experience any of these symptoms, you should tell your doctor immediately. "
Blood pressure should be measured before starting treatment.
In addition, the following undesirable events were observed during the post-marketing experience: alopecia, increased creatinine plasma levels, illusions, dyspnea, edema, fibrosis, abnormal liver function, hypersensitivity reactions, abnormal liver function, rash, respiratory conditions, respiratory failure and valvulopathy.
Rare cases of fibrosis in the lungs and heart have been reported that may cause cardiac valve dysfunction.
If any of the above side effects become serious, your doctor may decide to temporarily decrease the dose, then gradually increase it by half a tablet (0.25 mg carbergoline) per week (every 2 weeks). Adverse reactions may be diminished or may disappear.
overdose:
In case of accidental administration of a very high dose, severe side effects such as nausea, vomiting, headache, dizziness, high blood pressure or hallucinations may occur. In this situation, consult your doctor immediately.
Interactions with other drugs:
Use of other medicines
Some drugs, when taken at the same time as Dostinex, may influence the way Dostinex works, or Dostinex may influence the way these drugs work. Tell your doctor if you are on any of the following medicines:
- antiemetic (for anti-vomiting), such as metoclopramide;
- certain antibiotics, such as erythromycin;
- drugs to treat mental disorders or serious behavioral problems (eg phenothiazines, butyrophenones or thioxanthene);
- medicines known as ergot alkaloids (from the composition of certain medicines for the treatment of migraine, or ergotamine used to prevent or treat bleeding from abortion or the birth of a child).
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Use Dostinex with food and drink
Dostinex tablets can be taken regardless of meal schedule. However, to better support Dostinex treatment, it is advisable to take the tablets during a meal.
Pregnancy and breast-feeding:
If you do not want to become pregnant, you must use contraceptive methods recommended by your doctor. A pregnancy test may be required before starting treatment. If you become pregnant during treatment, stop treatment with Dostinex as soon as the pregnancy is confirmed. If you want to breast-feed, do not take Dostinex, because it affects the production of breast milk.
If you want to become pregnant, stop taking Dostinex a month before.
During treatment, it is advisable to perform rapid pregnancy tests or microscopic examination of the vaginal condition.
Ask your doctor or pharmacist for advice before taking any medicine.
Packaging presentation:
The tablets are white, capsular, "PU" engraved on one side and "700" on the other side and have a splitting groove.
Box with a brown glass bottle, containing 2 tablets
Box with a brown glass vial containing 8 tablets

Storage conditions:
Keep out of the reach and sight of children.
Do not store above 25 ° C.
Do not use Dostinex after the expiry date which is stated on the carton or the vial label. The expiry date refers to the last day of that month.
A desiccant material is attached to the inside of the lid. As the tablets absorb moisture, this desiccant should not be removed from the lid. For the same reason, after taking the tablet from the vial, screw the lid back in place; Also, do not put the tablets in another container.

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